The effectiveness of QuikClot brand hemostatic agent has been proven in extensive testing at the University of Connecticut , Hartford Hospital , the U.S. Marine War Fighting Lab, the Uniformed Services University of the Health Sciences (USUHS), and the Office of Naval Research (ONR).

USUHS conducted two comparative tests with other emergency hemostatic agents, using an arterial and venous groin injury model. Only QuikClot brand hemostatic agent reduced blood loss and increased survivability significantly better than the standard military bandage. In fact, only QuikClot brand hemostatic agent achieved 100% survivability.

The ONR research was designed and performed by Dr. Hasan Alam, a trauma surgeon and research specialist in the area of battlefield casualties. Dr. Alam is on the staff of the Washington (DC) Hospital Center and serves on the faculty of the USUHS.

Lieutenant Commander David Street of the Office of Naval Research, who helped to facilitate the research project, called QuikClot brand hemostatic agent "a major advance in casualty care".